Methyl 3-chloropropanimidate hydrochloride
Methyl 3-chloropropanimidate hydrochloride
CAS: 21367-88-4
Molecular Formula: C4H9Cl2NO
Methyl 3-chloropropanimidate hydrochloride - Names and Identifiers
Methyl 3-chloropropanimidate hydrochloride - Physico-chemical Properties
| Molecular Formula | C4H9Cl2NO |
| Molar Mass | 158.02636 |
| Melting Point | 93-94 °C |
| Sensitive | IRRITANT |
| MDL | MFCD10697994 |
Methyl 3-chloropropanimidate hydrochloride - Introduction
Methyl 3-chroopropimidate hydrochloride (hydrochloride) is an organic compound whose chemical formula is C4H8Cl2N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Solubility: Soluble in water and some organic solvents
-Melting point: about 130-132°C
-Chemical properties: It is an organic ester hydrochloride, which can participate in chemical reactions such as esterification and reduction reactions.
Use:
- Methyl 3-chloropanimidate hydrochloride is often used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize amino acids and peptide compounds as a protective group or reaction intermediate.
-It can also be used to synthesize compounds such as drugs and pesticides.
Preparation Method:
Methyl 3-chloropropanimidate hydrochloride can be synthesized by the following steps:
1. Obtaining 3-chloropropionimide.
2.3-Chloropropionimide was added to the hydrochloric acid carbonate solution.
3. Add methanol dropwise at low temperature until the sulfonic acid is completely converted to methyl ester.
4. Filtration or crystallization gives Methyl 3-chloropropanimate hydrochloride.
Safety Information:
- Methyl 3-chroopropimidate hydrochloride should be handled with appropriate laboratory safety measures, such as wearing gloves, safety glasses, etc.
-It may cause irritation and corrosion to the eyes, skin and respiratory tract, so contact with skin and eyes should be avoided and good ventilation should be provided during operation.
-If touched or eaten by mistake, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: Colorless crystalline solid
-Solubility: Soluble in water and some organic solvents
-Melting point: about 130-132°C
-Chemical properties: It is an organic ester hydrochloride, which can participate in chemical reactions such as esterification and reduction reactions.
Use:
- Methyl 3-chloropanimidate hydrochloride is often used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize amino acids and peptide compounds as a protective group or reaction intermediate.
-It can also be used to synthesize compounds such as drugs and pesticides.
Preparation Method:
Methyl 3-chloropropanimidate hydrochloride can be synthesized by the following steps:
1. Obtaining 3-chloropropionimide.
2.3-Chloropropionimide was added to the hydrochloric acid carbonate solution.
3. Add methanol dropwise at low temperature until the sulfonic acid is completely converted to methyl ester.
4. Filtration or crystallization gives Methyl 3-chloropropanimate hydrochloride.
Safety Information:
- Methyl 3-chroopropimidate hydrochloride should be handled with appropriate laboratory safety measures, such as wearing gloves, safety glasses, etc.
-It may cause irritation and corrosion to the eyes, skin and respiratory tract, so contact with skin and eyes should be avoided and good ventilation should be provided during operation.
-If touched or eaten by mistake, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 20:49:11
